Volume 13, Issue 2 (Jun & Jul 2019)
payavard 2019, 13(2): 134-141 |
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Sehat R, Shahabi Satlsar E, Hanachi P. Association between Iron, TIBC and Ferritin with Thyroid Hormones Levels in Patients Referred to Shouride Clinic Laboratory. payavard 2019; 13 (2) :134-141
URL: http://payavard.tums.ac.ir/article-1-6732-en.html
URL: http://payavard.tums.ac.ir/article-1-6732-en.html
1- Master of Student in Biochemistry, Biotechnology Departments, Faculty of Biology, Alzahra University, Tehran, Iran , ro_sehat@yahoo.com
2- Ph.D. candidate in Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
3- Associate Professor, Biotechnology Departments, Faculty of Biology, Alzahra University, Tehran, Iran
2- Ph.D. candidate in Paramedical Sciences, Shahid Beheshti University of Medical Sciences, Tehran, Iran
3- Associate Professor, Biotechnology Departments, Faculty of Biology, Alzahra University, Tehran, Iran
Abstract: (3883 Views)
Background and Aim: Iron deficiency is one of the most common nutritional disorders in the world, and it may affect the metabolism and function of a number of proteins, including the level of thyroid hormones. As such, fluctuations in the level of thyroid hormones may also affect the body's iron status. The present study aimed to evaluate the relationship between thyroid hormones and the status of iron stores.
Materials and Methods: The study populations included referral patients to laboratory of Shourideh clinic in Mashhad, Iran. Fe, Ferritin, TIBC (total iron-binding capacity), TSH, T4, T3, and CRP tests were performed with a physician's request. The target sample size was a total of 420 patients including 287 women and 133 men with an average age of 41.5 years. TSH and Ferritin test were measured by Elisa method, Fe and TIBC were measured by automated method.
Results: The results showed no significant relationship between the body's iron status and thyroid hormones level (P˃0.05). Interestingly, in subjects with lower iron level, TSH was at the highest level and T4 was at the lowest level. However, no positive relationship was found between iron status and T3 level.
Conclusion: Although, there was no significant relationship between iron status and thyroid hormones level in the present study, it seems that the fluctuations of each of them may affect somehow the other.
Materials and Methods: The study populations included referral patients to laboratory of Shourideh clinic in Mashhad, Iran. Fe, Ferritin, TIBC (total iron-binding capacity), TSH, T4, T3, and CRP tests were performed with a physician's request. The target sample size was a total of 420 patients including 287 women and 133 men with an average age of 41.5 years. TSH and Ferritin test were measured by Elisa method, Fe and TIBC were measured by automated method.
Results: The results showed no significant relationship between the body's iron status and thyroid hormones level (P˃0.05). Interestingly, in subjects with lower iron level, TSH was at the highest level and T4 was at the lowest level. However, no positive relationship was found between iron status and T3 level.
Conclusion: Although, there was no significant relationship between iron status and thyroid hormones level in the present study, it seems that the fluctuations of each of them may affect somehow the other.
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