Volume 19, Issue 4 (11-2025)
payavard 2025, 19(4): 297-310 |
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Nabiolahi A, Keikha N. New Applications of Point of Care Tests (POCTs) in Health Care: A Scoping Review. payavard 2025; 19 (4) :297-310
URL: http://payavard.tums.ac.ir/article-1-7935-en.html
URL: http://payavard.tums.ac.ir/article-1-7935-en.html
1- Assistant Professor, Department of Medical Library and Information Science, School of Allied Medical Sciences, Zahedan University of Medical Sciences, Zahedan, Iran
2- Associate Professor, Infectious Diseases and Tropical Medicine Research Center, Research Institute of Cellular and Molecular Sciences in Infectious Diseases, Zahedan University of Medical Sciences, Zahedan, Iran ,nasserkeikha@zaums.ac.ir
2- Associate Professor, Infectious Diseases and Tropical Medicine Research Center, Research Institute of Cellular and Molecular Sciences in Infectious Diseases, Zahedan University of Medical Sciences, Zahedan, Iran ,
Abstract: (1413 Views)
Background and Aim: Point of Care Tests (POCTs) are a laboratory diagnostic system that can be performed at the patient care location and help diagnose diseases quickly. Due to the increase in population, the prevalence of contagious diseases, none access of society members to laboratories, the global need for the availability of modern diagnostic and health technologies at the place of patient care, the aim of research was to explore new aspects of the application of Point of Care Tests to patients as well as the process of developing these technologies in the field of healthcare.
Materials and Methods: A scoping review method were applied by determining the key words through medical subject headings and related articles, searching in the databases of Web of Science, Scopus and PubMed databases as well as Google Scholar, Google and Magiran and Scientific information database. Furthermore to preserve the variety of sources and articles, the criteria for entering the study were English-language articles and no time limit was applied.
Results: Most of the 17 related articles were reviews. The most common technologies in POCTs were lateral flow assays (LFA) that applied to diagnosis of Cryptococcus fungal infection, tuberculosis, hepatitis, legionella, malaria and covid-19, and nucleic acid amplification tests have helped to detect viruses and bacteria using DNA and RNA. From NAAT (Nucleic Acid Amplification Tests) based on microsialate, it can be referred to RT-PCR (Reverse transcription- polymerase chain reactio) and LAMP oop-Mediated- Isothermal Amplification (LAMP), where in recent years are widely used for detection of infectious diseases specially SARS-CoV-19. Additional basic diagnostic tools have focused on Small handheld, POCT devices with a monitoring device, cartridge, and other devices; whereas in the new generations, special focus were on quality assurance, microfluidics, Nano-biosensors and smart phones.
Conclusion: The analysis of published studies showed that the diagnostic tools of tests on POCTs are expanding and have been able to provide better clinical and economic results. In addition to the extensive use of two advanced types of lateral flow assays and nucleic acid amplification tests to diagnose tests at the patient’s bedside; Microfluidics, Nano biosensors and smart phones have also expanded. Quality assurance also requires the determination of accurate quality management procedures, policy programming and necessary policy formulation by officials to achieve reliable results for patient care.
Materials and Methods: A scoping review method were applied by determining the key words through medical subject headings and related articles, searching in the databases of Web of Science, Scopus and PubMed databases as well as Google Scholar, Google and Magiran and Scientific information database. Furthermore to preserve the variety of sources and articles, the criteria for entering the study were English-language articles and no time limit was applied.
Results: Most of the 17 related articles were reviews. The most common technologies in POCTs were lateral flow assays (LFA) that applied to diagnosis of Cryptococcus fungal infection, tuberculosis, hepatitis, legionella, malaria and covid-19, and nucleic acid amplification tests have helped to detect viruses and bacteria using DNA and RNA. From NAAT (Nucleic Acid Amplification Tests) based on microsialate, it can be referred to RT-PCR (Reverse transcription- polymerase chain reactio) and LAMP oop-Mediated- Isothermal Amplification (LAMP), where in recent years are widely used for detection of infectious diseases specially SARS-CoV-19. Additional basic diagnostic tools have focused on Small handheld, POCT devices with a monitoring device, cartridge, and other devices; whereas in the new generations, special focus were on quality assurance, microfluidics, Nano-biosensors and smart phones.
Conclusion: The analysis of published studies showed that the diagnostic tools of tests on POCTs are expanding and have been able to provide better clinical and economic results. In addition to the extensive use of two advanced types of lateral flow assays and nucleic acid amplification tests to diagnose tests at the patient’s bedside; Microfluidics, Nano biosensors and smart phones have also expanded. Quality assurance also requires the determination of accurate quality management procedures, policy programming and necessary policy formulation by officials to achieve reliable results for patient care.
Keywords: Point-of-Care Testing, Lateral Flow Assays, Nucleic Acid Amplification Techniques (NAATs), Microfluidics, Nano Biosensors, Smartphone
Type of Study: Review |
Subject:
Laboratory Sciences
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