Volume 4, Number 3 and 4 (20 2011) | payavard 2011, 4(3 and 4): 60-66 | Back to browse issues page


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Rahimkhani M, Einollani N, Sharifian R. Survey Of Relationship Between Serum Procalcitonin And Infectious Diseases. payavard. 2011; 4 (3 and 4) :60-66
URL: http://payavard.tums.ac.ir/article-1-95-en.html

Abstract:   (3624 Views)

Background and Aim: Procalcitonin is prohormone of calcitonin and is made 116 amino acids. The normal value of procalcitonin is less than 0.5 ng/ml, that if this amount exceeds, infection is indicated. This poly-peptide is a marker for the diagnosis of primary infection. Increased amounts of procalcitonin is associated with infection especially bacterial infections.

Materials and Methods: 32 patients with liver cirrhosis and 16 healthy controls enrolled in this study were. Serum PCT levels in these subjects was measured. PCT level was measured by semi-quantitative method.

Results: Patient group included 23 males and nine females with mean age of 45 years and SD= 17.44 years, the control group included 11 males and 5 females with mean age of 46 years and SD=15.5 years.
The statistical analysis showed that there was significant difference between PCT levels in patients and controls (P<0.05).Furthermore PCT levels was significantly hgher in cirrhotic patients with hepatitisec background.

Conclusion: Since these patients had no symptoms of infection and were hospitalized for endoscopy test and the PCT test was positive in 78.1% of cirrhotic patients ,whereas this ratio was 25% in the control group, the patients probably were infected and should be under proper treatment.

Full-Text [PDF 406 kb]   (856 Downloads)    
Type of Study: Research | Subject: Hospital Managment
Received: 2010/07/20 | Accepted: 2010/11/23 | Published: 2013/07/29

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