Volume 1, Number 1 (9 2007)                   payavard 2007, 1(1): 8-16 | Back to browse issues page


XML Persian Abstract Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Choobineh H, Alizadeh S, Sharifi yazdi M, Vaezzadeh F, Dargahi H, Pourfatolah A. The effect of repeated transfusions on active cytomegalovirus infection, in the presence of IgM, in patients with thalassemia major in Iran. payavard. 2007; 1 (1) :8-16
URL: http://payavard.tums.ac.ir/article-1-166-en.html

Abstract:   (6744 Views)

Background: With due attention to the prevalence of thalassemia in Iran and patients' importunate needs for blood intake, this study aimed to inspect contaminations due to repeated blood transfusion which does not sift in blood donation. One such contamination is cytomegalovirus infection, which is an important pathogen in immunosuppressive patients or receivers of transplanted organs.

Methods: This cross sectional study was conducted on 311 thalassemia patients under age of 15 yr who was receiving blood from Hospitals in Tehran and Noorabad Mamasani repeatedly. To determine active infection (presence of IgM antibodies) of cytomegalovirus, ELISA method was used. In addi­tion, 225 healthy people under age of 15 yr were studied as testified group and finally all data were analyzed using SPSS ver. 11.5.

Results: 12.9 % of patients were positive from the view point of active infection. Regional separation of patients showed that the patients resided in Tehran are more contaminated to this virus than patients of other cities.

Conclusion: The range of cytomegalovirus active infection in thalassemia patients is high. One reason might be the infected blood intake or immunosuppressant (weakness of immune system) in patients, there­fore immunity care of these patients and negative serologic blood intake with respect to and also he­matic parents (parents with the same blood) are important.

Full-Text [PDF 163 kb]   (1451 Downloads)    
Type of Study: Research | Subject: Hospital Managment
Received: 2006/10/2 | Accepted: 2007/09/16 | Published: 2013/07/24

Add your comments about this article : Your username or email:
Write the security code in the box

© 2017 All Rights Reserved | Journal of Payavard Salamat

Designed & Developed by : Yektaweb